PRX at Madison’s Radiance Skin Therapy & Laser Center is a topical collagen-stimulating skin treatment often called the “No-Peel Peel.” It improves skin firmness, texture, tone, and radiance without significant visible peeling or downtime. It is commonly used on the face, neck, chest, and hands. PRX is ideal for patients seeking advanced skin rejuvenation treatments in 2026 without needles, aggressive exfoliation, or recovery time.
Unlike traditional chemical peels, this treatment works deeper within the skin without significant visible peeling or extended downtime. PRX is ideal for patients who want noticeable skin rejuvenation without needles, aggressive peeling, or prolonged recovery.
Book a PRX consultation in Madison, WI, at Radiance Skin Therapy & Laser Center to determine if this collagen-boosting treatment is right for your skin goals. Call (608) 240-0088 to schedule your consult or book online.
PRX is a topical biostimulator that combines:
This unique formulation allows the treatment to penetrate deeply into the skin to stimulate collagen and elastin production while minimizing surface irritation and visible exfoliation.
The result is skin that appears:
PRX Skin Booster Serum is safe for many skin types and can be performed year-round with appropriate sun protection.
PRX includes specialized formulations designed to address different levels of skin aging, texture concerns, and pigmentation issues.
PRX Derm Perfexion is best suited for patients seeking overall skin rejuvenation and prevention of early signs of aging.
It may be recommended for:
PRX-Plus is formulated for more intensive skin concerns requiring deeper correction and brightening support.
It may be recommended for:
Traditional chemical peels primarily work by creating visible exfoliation at the surface of the skin.
PRX Skin Booster Serum works differently.
Rather than focusing on aggressive peeling, PRX stimulates skin regeneration beneath the surface while minimizing visible flaking and downtime. Patients often experience smoother, more hydrated, glowing skin with little interruption to daily activities.
Many patients choose this treatment because they want:
PRX can be used on multiple areas of the body, including:
The neck and chest are especially popular treatment areas, as it can help improve the appearance of crepey skin and sun damage with minimal downtime.
During treatment, the solution is massaged into the skin in layers using a specialized technique. Patients may experience a mild tingling or warming sensation during application.
Treatment is typically well-tolerated, and appointments are relatively quick.
After treatment, many patients notice:
Some patients may experience mild tightness, dryness, or light flaking for several days, though significant peeling is uncommon.
Treatment recommendations vary depending on skin concerns and goals.
Many patients benefit from a series of treatments for optimal collagen stimulation and skin rejuvenation. Maintenance treatments may also be recommended to help support long-term skin quality.
Your provider at Radiance will customize a treatment plan based on your skin condition, concerns, and desired outcome.
At Radiance, PRX Skin Booster Serum is often incorporated into a comprehensive skin rejuvenation plan.
Depending on your concerns, it may be paired with treatments such as:
Our approach focuses on improving overall skin quality and supporting long-term collagen health—not simplytreating isolated lines or wrinkles.
At Radiance Skin Therapy & Laser Center, treatments are designed with a focus on personalized, medically guided aesthetic care that enhances skin health while maintaining natural-looking results.
Led by Anne Pientka, RN, BSN, owner of Radiance Skin Therapy & Laser Center (Madison, WI), our practice is built on decades of clinical experience, advanced aesthetic training, and a commitment to balanced, natural outcomes. Anne is a member of the ASPSN, CSASN, and the Wisconsin Nurses Association, and has served as a clinical trainer for leading aesthetic companies, including Allergan (2013–2023) and Revanesse (2022–2024).
Our approach combines:
This allows us to create individualized treatment plans that prioritize skin quality, long-term improvement, and overall facial harmony.
Under Anne’s leadership, Radiance emphasizes continuous education and evolving clinical techniques to ensure patients receive results that look refreshed, natural, and never overdone.

Achieve smoother, firmer, more radiant skin without significant downtime. Book a PRX consultation at Madison, WI’s Radiance Skin Therapy & Laser Center to find out if this collagen-boosting treatment is right for you. Call 608.240.0088 to schedule your consult or book online.
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